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Some people with advanced kidney dysfunction report a metallic or unpleasant taste.
Waste products accumulating in the blood can alter taste and appetite.
However, medications, dental problems, infections, and reflux can produce similar sensations.
## 12. Bad Breath
Advanced kidney disease can occasionally cause an ammonia-like or unusual breath odor.
But chronic bad breath is much more commonly related to:
* Gum disease
* Dry mouth
* Dental problems
* Sinus issues
* Reflux
Persistent breath changes should be evaluated according to the full clinical picture.
## 13. Loss of Appetite
Poor appetite may develop as kidney disease becomes more advanced.
Possible symptoms can include:
* Feeling full quickly
* Food tasting different
* Nausea
* Reduced interest in eating
Unexplained appetite loss has many potential causes and should not be attributed to the kidneys without testing.
## 14. Nausea or Vomiting
Waste buildup in advanced kidney disease can contribute to gastrointestinal symptoms.
Persistent nausea or vomiting can also occur with:
* Infection
* Medication effects
* Digestive disease
* Migraine
* Pregnancy
Repeated vomiting can itself cause dehydration and worsen kidney function.
## 15. Unexplained Weight Changes
Kidney problems can sometimes cause:
