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* Weight loss from poor appetite
* Weight gain from fluid retention
A rapid increase in weight over a few days may reflect fluid buildup rather than body fat.
## 16. Shortness of Breath
Kidney disease can contribute to breathlessness if fluid accumulates in the lungs or if severe anemia develops.
Shortness of breath can also signal heart or lung disease and should never simply be assumed to come from the kidneys.
Sudden severe breathing difficulty requires urgent medical attention.
## 17. Trouble Concentrating
Anemia and the buildup of waste products in advanced kidney disease may contribute to:
* Brain fog
* Poor concentration
* Mental fatigue
* Confusion
Sudden confusion is an emergency symptom and has many possible causes.
## 18. Feeling Cold All the Time
Anemia can make some people feel unusually cold, even when the room temperature is comfortable.
Kidney disease can contribute to anemia because damaged kidneys may produce less erythropoietin, a hormone involved in red blood cell production.
## 19. Restless Legs
