23 Strange Signs Your Kidneys Might Be in Trouble

Kidney disease cannot be reliably diagnosed from symptoms alone.

Healthcare professionals commonly use:

### Blood Tests

Creatinine levels are used to estimate how effectively the kidneys filter the blood, often reported as **eGFR**.

### Urine Tests

Urine testing can detect albumin or other proteins that may indicate kidney damage.

One abnormal result does not always mean chronic kidney disease. Tests may need to be repeated over time.

## When to Contact a Healthcare Professional

Arrange medical evaluation if you experience persistent:

* swelling
* blood in the urine
* significant changes in urination
* unexplained fatigue
* recurrent nausea
* unexplained weight loss
* persistent foamy urine

Seek urgent medical attention for severe shortness of breath, chest pain, confusion, or a sudden major decrease in urine output.

## The Bottom Line

Kidney problems can produce a surprisingly wide range of symptoms, from swelling and urine changes to itching, cramps, appetite loss, fatigue, and difficulty concentrating.

But most of these symptoms are **not specific to kidney disease**, and early kidney disease may cause no symptoms at all.

If you have risk factors or persistent changes that concern you, simple blood and urine tests can provide much more reliable information about kidney function than symptoms alone.

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